Harold Andrew "Duke" Dejan (February 4, 1909 – July 5, 2002) was an American jazz alto saxophonist and bandleader in New Orleans.

Born into a Creole family in New Orleans, he took clarinet lessons as a child before switching to saxophone, and became a professional musician in his teens, joining the Olympia Serenaders and then the Holy Ghost Brass Band.

He also worked in the mail office of the Lykes Brothers Steamship Company for 23 years and played in Navy bands during World War II.

The band appeared in the James Bond movie Live and Let Die, and in many TV commercials.

[1] In 1991 Dejan suffered a stroke, which left him unable to play the saxophone, but he continued as a band leader and singer until shortly before his death.