In the early 1700s, John Strype described the street as "generally taken up by eminent Tradesmen, as Mercers, Lacemen, Drapers, etc".
In 1763, Thomas Mortimer's The Universal Director recorded that there were twelve residents, who included three artists, a baker, a surgeon, a linen draper, two stockbrokers, a mercer and three apothecaries.
[2] By the 1870s the street had become the home of a number of publishing firms and in 1874 The Builder described it as "fast becoming the Paternoster-row of the West End".
[4] Among publishers, Williams and Norgate had their offices at number 14 and in the twentieth century Victor Gollancz were in the street.
More recently, Greenwood Publishing Group and Dorling Kindersley have had offices in Henrietta Street.
In 1885, the Theatrical Mission opened Macready House as a club for vulnerable young women working in the nearby London theatres.
[8] Number 25–29 on the north side is the former St. Peter's Hospital which is grade II listed[9] and the largest building in the street.