Henry Rufus Pierson (June 13, 1819 – January 1, 1890) was an American lawyer and politician from New York.
Then he studied law, first in Cherry Valley, then in New York City, was admitted to the bar in 1848, and practiced.
He was an Alderman (3rd Ward) of Brooklyn from 1858 to 1860, and was President of the Board of Aldermen.
In 1869, he went to Chicago as Financial Agent of the North Western Railroad, and was the company's vice president for two years.
He died from the Russian flu at his home in Albany, and was buried at the Green-Wood Cemetery in Brooklyn.