Henry Titus Welles (April 3, 1821 – March 4, 1898) was a lawyer, businessman and Democratic politician who served as the first mayor of St. Anthony, Minnesota.

[1] He grew up working on the family's farm and later attended Trinity College, graduating in 1843.

He relocated to the young city of St. Anthony and went into the lumber business with Franklin Steele.

In that same year he and Steele built the first major bridge crossing the Mississippi between what was then the two towns of St. Anthony and Minneapolis.

[2] Outside of Minneapolis and St. Anthony Welles also owned significant real estate in the towns of St.