The Shire of Hepburn is a local government area in Victoria, Australia, located in the central part of the state.

It covers an area of 1,473 square kilometres (569 sq mi) and, in the 2021 Census the shire had a population of 16,604.

[1] It includes the towns of Clunes, Creswick, Daylesford, Hepburn Springs and Trentham and the villages of Glenlyon, Allendale, Kingston, Leonard's Hill, Lyonville, Newlyn, Denver and Smeaton.

The shire is named after an early squatter named John Hepburn, who established the Smeaton Hill pastoral run, which was located a few kilometres north of present-day Creswick.

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