Hephzibah is a poetic name used in the Book of Isaiah (62:4) to refer to Jerusalem, meaning "My delight is in Her."

The prominence of these new religious institutions in the area swayed the state of Georgia to rename the town Hephzibah in 1870.

[3] In 1909, Walter A. Clark published a book of local history, named A Lost Arcadia - The Story of My Old Community, detailing the earliest days of Hephzibah.

The residents of Hephzibah and nearby Blythe voted to maintain their separate city governments prior to this action.

[11] This list includes people who were born in Hephzibah or who spent a significant amount of time living in the town.