Hermann Senator (6 December 1834 – 14 July 1911) was a German internist who was a native of Gnesen in the Prussian Province of Posen (now Gniezno, Wielkopolska, Poland).

After the death of Friedrich Theodor von Frerichs (1819-1885), he served as head of the "first medical clinic" at Berlin for a few months.

Hermann Senator made several contributions in internal medicine, in particular, involving research in the field of nephrology.

[2] His treatise on diseases of the kidneys, "Die Erkrankungen der Nieren", was included in Nothnagel's textbook of special pathology and therapy.

In 1868 he introduced his theory of "autointoxication", of which he speculated that "self-infection" originating in the intestines could be a source of disease elsewhere in the human body.