"[9][10] The series is The Boys version of the big 'event' storylines but, according to Ennis "while we're having a pop at the notion of mass crossovers within a shared universe, we're not picking on 'Crisis' or 'Secret Wars' or 'Countdown' or whatever in particular.

[11]Herogasm starts off with the Homelander making a public announcement that the heroes and villains of the world have united to face an alien threat, which was responsible for destroying the G-Men.

They drug and throw Doofer from the Fantastico, a parody team of the Fantastic Four, off the hotel's roof to create a distraction, then abduct Agent Lucero from the Vice President's security detail.

During the Super Hero award ceremony, a prostitute attempts to keep the Vought Guy occupied at a bar, but he quickly discerns her true intentions and demands to know who hired her.

Godfrey, The Vice-President's Chief of Staff who works for Vought, overhears Agent Lucero saying he might have done something to fix the problem with Red River members infilitrating the security detail, and he orders a search of the island.

The series has been collected into a trade paperback: In January 2021, Eric Kripke, the showrunner of the Amazon Prime Video streaming television adaptation of The Boys, confirmed that Herogasm would be adapted as the sixth episode of the series' third season, featuring Jensen Ackles portraying Soldier Boy, a character introduced in Herogasm.

In 2017, CBR ranked Herogasm as the comic book showing the fourth-most nudity in the 2000s, praising its depiction of "bedroom proclivities that rival their inhuman abilities.

"[12][13] Will Morgan of The Slings & Arrows praised the "overall tone [a]s gleeful, as Ennis strives for ever more depraved and ludicrous situations for the series’ colour-splashed supporting cast to get into, taking irreverent jabs at the Avengers, the Fantastic Four, several of Batman's Rogue's Gallery, and scores more.

Artist John McCrea's talent for amiable goonery has seldom been deployed to better effect; even the most horrible and heinous acts are presented with a chirpy patina which offsets the darker scenes masterfully.