[7] Assembling a "citadel of science" designed by German scientist Horace Grayson (father of the future Marvel Boy) and built by Moloid slaves supplied by Phaeder, the pair continued their experiment until Drew's daughter fell ill from uranium poisoning and was placed into suspended animation to save her life.

[9] Now joined in his work by research assistant Miles Warren (who would later become Jackal), Wyndham was able to make more and more radical breakthroughs, including the genetic acceleration of some local animals into the half-human, half-animal beings that he dubbed his "New Men".

[10] When Jonathan Drew returned to Wundagore where he was possessed by the ghost of the 6th-century magician Magnus, he warned that the citadel had been constructed upon the place where the malevolent Elder God Chthon had been banished.

He began to train the New Men in the ways of combat and chivalry of his time until they eventually came to refer to themselves as the "Knights of Wundagore", and to Wyndham as the "Lord High Evolutionary".

[10][11] In 1958, Magnus's fears came to pass when Baron Russoff attempted to use the ancient magical tome known as the Darkhold to cure himself of his lycanthropy, inadvertently freeing Chthon from imprisonment.

Raised by Roma Django and Marya Maximoff, the twins grew up to be the superheroes Quicksilver and the Scarlet Witch, the latter wielding chaos magic as a result of Chthon's influence.

When the High Evolutionary arrived at the Beyonders' planet museum, he himself reported that his mind snapped when he witnessed the scope of their powers and how effectively insignificant he was compared to these alien beings.

For unknown reasons, the Beyonders placed all life on Counter-Earth into stasis[volume & issue needed] and later allowed the planet to be destroyed during the Infinity Gauntlet conflict, although they could easily have prevented it.

[22] The High Evolutionary later came into conflict with a number of superheroes, notably the reserve Avengers and Adam Warlock, when he tried to forcibly mutate (or "evolve") the entire population of the Earth with his "Evolution Bomb".

He and his creations were on-hand to witness the birth of a new Celestial, but viewing this event with all his hyper-evolved senses seemed to drive the High Evolutionary back to madness.

[volume & issue needed] The High Evolutionary repented, agreeing to return Shanna to her normal state once he realized (despite his mania) that the relationship should not be pursued.

[volume & issue needed] The High Evolutionary once helped to restore the Savage Land and its inhabitants after the engines that kept the volcanoes active were demolished by Terminus.

[volume & issue needed] He was seen in the X-Men: Endangered Species one-shot as one of the nine villains Beast approaches to help him reverse the effects of M-Day.

[30] After extensively examining the Dreaming Celestial, the High Evolutionary subjected Magneto to an extremely dangerous technological procedure in an attempt to restore his power and was a success.

The Surfer and the Fantastic Four unite with the armed forces to kill all the High Evolutionary's creations on the grounds that they eradicate emotion and individuality from the humans who were transformed.

He was served in his plans by a human called the Master Scientist and Luminous (a female who was created from the genetic templates of Quicksilver and Scarlet Witch while also having the same abilities as them).

As a result of this action, the Earth-1610 Ultimates members Captain America, Iron Man, Giant-Man, Wasp, and Hulk were revived where they were to help Eternity fight the First Firmament.

[47] In a flashback, the High Evolutionary once visited Madame Monstrosity's Farm where he is shown a demonstration on how her Humanimal project works by fusing a plumber with a crab.

Once teleported away from Spider-Boy, Madame Monstrosity learned that the High Evolutionary only saved her because she became the ultimate oddity made from the different animal DNA samples in her as he begins his first round of tests with her.

[50] He is considered the leading geneticist in the Marvel universe, and is vastly knowledgeable in biology, chemistry, medicine, physics, engineering, human psychology, computer science, and cybernetics.

Due to experimentation on his own genome, his highly enhanced brain and cybernetic exoskeleton, the High Evolutionary has demonstrated god-like powers; including the ability to evolve and devolve life-forms, superhuman strength and durability, manipulating matter at a subatomic level, energy manipulation and projection, cosmic awareness, precognition, telepathy, telekinesis, extra-dimensional travel, and size alteration.

[51] Of note, the High Evolutionary has forged weapons for his New Men that show some anti-mystical properties, as demonstrated by a lance wielded by Beast that was actually able to damage the Darkhold.

He has great respect for the process of evolution, but is also deeply troubled by the immense amount of death and suffering required for such slow progress (see the Quicksilver series).

The High Evolutionary has been manipulated and driven to insanity by both the Beyonders and the Celestials, cosmic races that have interfered with human evolution in the past, indicating that his work might perhaps be a threat to their own.

He has served as a benevolent father figure to several characters, including Adam Warlock, Quicksilver, Spider-Woman, Wolverine, and Thor, often charging them with tasks that lead to their personal growth as individuals and heroes.

At times the High Evolutionary has feigned indifference to the fate of others when his own safety is at stake, only to reveal a considerably more benign agenda later (see the Annihilation: Conquest series).

[53] He gave Magda shelter from the elements without hesitation,[12] risked death to fight Galactus over Counter-Earth,[51] and literally begged Ka-Zar not to poison the Earth's biosphere with Isotope E out of compassion for the suffering it would cause.

[55] Though made personally wealthy by uranium deposits, the High Evolutionary has also provided for a generous financial trust for the people of Transia, ensuring economic stability for the nation.

Seeking to improve what he considers lower lifeforms, he created the Humanimals of Counter-Earth from Earth animals, the Sovereign, and Half-worlders such as Batch 89, which included 89P13 / Rocket.

After Rocket chooses to spare his creator's life while rescuing his experiments, Drax carries the High Evolutionary from his exploding ship to be imprisoned on Knowhere.