The highway begins at the Minnesota state line along the St. Croix River as a continuation of MIN 48 and runs east from it.

The highway passes by a large amount of lakes and then curves to the north, meeting US 53 and its business route in Minong.

[2] After its concurrency with WIS 27 starts, the highway meets Smith Lake and curves to the south, running towards Hayward.

The highway then runs east-northeast passing through Tyler Forks, Rouse, and Upson, where it meets WIS 122.

The highway continues east into Hurley and terminates at US 51 west of the Michigan state line along the Montreal River.