[5] The Holy Cross High School campus maintains a campus-wide WiFi signal; a library; a large instrumental and choral music room with adjacent practice rooms; science labs; a foreign language lab; a guidance complex; The Blasius Family auditorium, which seats ~750;[6] a full-service cafeteria; the Timothy J. McDonald Gymnasium; the Stephen J. Ross Fitness Center;[7] and digital classrooms and art studios in the Alex Family Gallery Art and Technology Center.

The original plans were designed to accommodate 1,200 students, parking for 400 cars, and facilities for an extensive physical education program.

Brother Robert Fontaine coordinated the opening of the new high school, eventually serving as its first guidance counselor.

On October 7, 1968, Holy Cross High School officially opened its doors at the newly built facility.

[10] Once admitted, students have the opportunity to take proficiency tests in mathematics and/or foreign language to advance their freshman year placing (Ex.

The Brothers of Holy Cross, Eastern Province, continue Basil Moreau's vision through sponsorship and staffing of the school, in association with the Sisters of the Congregation of Notre Dame and many dedicated lay men and women, many of whom hold advanced degrees and/or certificates of advanced study.

The various levels offer students the ability to challenge themselves beyond standard coursework, while achieving a higher Adjusted Grade Point Average.

Holy Cross is a member of the Naugatuck Valley League and the Connecticut Interscholastic Athletic Council.

The Holy Cross athletic program is respected statewide for its competitiveness and the positive attitudes and good sportsmanship of its players and coaches.

In 2023, Director of Campus Ministry Kyle Piatak pioneered Holy Cross's E-Sports program, featuring a variety of competitive-style games such as Rocket League and Mario Kart 8.

After cancellations in 2020 and 2021, the Crusaders defended their state title in a win over runner-up, Woodland Regional High School, 546–541.5.

The loyal fans of Holy Cross' basketball and football programs travel around the state to turn any game into a 'home' atmosphere for the teams.

Student activities offer the opportunity to explore lessons presented in class, learn new skills and develop leadership ability.

The student government at Holy Cross includes an executive board made of four elected class officers from each class, a liaison from the Presidents' Council, a liaison from the Athletic Council, and seven members of the Senior Life Board appointed by the institution's administration.