The 1910 Holy Rosary Hospital, with its 1922 annex, is located on Clarke and Jordan Streets, northeast of Mile City's Main Street Historic District, and approximately 1/3 mile east of the Ursuline Convent of the Sacred Heart.

Tree-lined residential neighborhoods fringe the property to the south, while Leighton Avenue, a busy transportation corridor, defines its northern boundary.

[2] The Holy Rosary Church underwent an extensive restoration and has been converted to low income housing.

Green asphalt shingles cover the roof, and large metal ventilators pierce the ridgeline.

A Mission-style curvilinear parapet rises across the entry bay at attic level on the west (front) elevation, a hipped-roof dormer protrudes from the center of the north slope, and another hipped roof covers the central, protruding bay of the east elevation.