(NBE) Holy Spirit Hospital is a Charitable Trust Hospital located in Andheri, Mumbai, owned and managed by the Missionary Sisters Servants of the Holy Spirit, which began in 1964 as an out-patient clinic.

In 1964, four nuns from the Netherlands-based Missionary Sisters Servants of the Holy Spirit established an outpatient medication dispensary under a tree in Andheri.

By 1967 they had developed a 65-bed hospital which eventually grew to a comprehensive 300-bed facility.

[2][3] Later, a dirt track path between the Mahakali Caves and the hospital was replaced by a road extension from Chakala.

BEST provided a twice-daily bus service at the hospital's request.