In the mid-1930s, the Civilian Conservation Corps (CCC) began reforestation of the area and developing a system of roadways and recreational areas.

In descending order of land area the forest is located in parts of: The flora of the Homochitto National Forest consists of about 850 species of vascular plants.

[5][6] Three species of winter stoneflies have been collected from the Homochitto National Forest,[7] including one that was later described as a new species, Allocapnia starki.

There are local ranger district offices located in Meadville.

This article related to a protected area in Mississippi is a stub.