Honduras competed at the 2012 Summer Olympics in London, United Kingdom, from 27 July to 12 August 2012.

Comité Olímpico Hondureño sent the nation's largest delegation to the Games, two more than Beijing.

Most of them qualified in men's football, the only team sport the nation's competed in at these Olympic games.

The Honduran team also featured two hurdlers, Jeimy Bernárdez, who competed at her second consecutive Olympics, and Ronald Bennett, who was the nation's flag bearer at the opening ceremony.

Among the sports, Honduras made its Olympic debut in shooting, specifically in the women's pistol event.