The Hospital of the Holy Spirit in Warsaw (Szpital Świętego Ducha w Warszawie) was a hospital originally built in 1442, at the church of St. Martin's at Piwna Street in Warsaw's Old Town.

It was founded by Anna Fiodorówna (a princess of the Duchy of Masovia) as a shelter for the poor.

The building at 12 Elektoralna Street was built between 1859 and 1861 according to a neo-Renaissance design by Józef Orlowski.

Before the war, the medical clinic was run by Vilém Dušan Lambl with Samuel Goldflam as his assistant.

First, occupied by trade unions, it later housed the Warsaw Cultural Centre (Warszawski Ośrodek Kultury).