This non-coding RNA was identified in Neisseria meningitidis and is involved in iron regulation of the succinate dehydrogenase genes sdhA and sdhC.

[1][2] NrrF acts as an antisense RNA and is complementary to the junction between the second and third genes of the sdh operon (sdhD and sdhA).

Secondary structure predictions have indicated that this interaction occurs in a single stranded loop region of the NrrF RNA.

The RNA chaperone Hfq acts to enhance binding of NrrF or stabilizes the NrrF/sdh transcript duplex.

Another NrrF RNA target is mRNA petABC, coding for cytochrome bc1 ( an essential components of the N. meningitidis respiratory chain).