Hubble Creek is a stream in Cape Girardeau County, Missouri in the United States.
The stream flows south passing under I-55 at the intersection with US Route 61.
The stream runs parallel to Route 61 through Jackson and continues south past the communities of Gordonville and Dutchtown to its confluence with the Castor River Diversion Channel[2] at 37°14′01″N 89°40′28″W / 37.23361°N 89.67444°W / 37.23361; -89.67444.
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