Part of the Quebrada de Humahuaca extends through the length of the department.

Humahuaca Department has a surface area of 3,792 square kilometres (1,464 sq mi), and as of the 2010 census had a population density of 4.6 inhabitants per square kilometer.

[1] The department is bordered on the east by the province of Salta, on the west by Cochinoca Department, and on the south by the Tumbaya, Tilcara, and Valle Grande Departments.

[2] The primary means of accessing the department is via National Route 9.

This article about a place in Jujuy Province, Argentina is a stub.