[3] The BCM-HGSC collaborated with researchers at the U.S. Department of Energy's Lawrence Berkeley National Laboratory and Celera Genomics to sequence the first species of fruit fly, Drosophila melanogaster.
[4] The BCM-HGSC also completed the second species of fruit fly (Drosophila pseudoobscura),[5] the honeybee (Apis mellifera),[6] and led an international consortium to sequence the brown Norway rat.
[7] The BCM-HGSC subsequently sequenced and annotated the genome of the cow (Bos taurus), the sea urchin, rhesus macaque, tammar wallaby, Dictyostelium discoideum, and a number of bacteria that cause serious infections (Rickettsia typhi, Enterococcus faecium, Mannheimia haemolytica, and Fusobacterium nucleatum).
The BCM-HGSC was a major contributor to the Mammalian Gene Collection program,[8] to sequence all human cDNAs, as well as the International Haplotype Mapping Project (HapMap).
[citation needed] Other research within the BCM-HGSC includes new molecular technologies for mapping and sequencing, novel chemistries for DNA tagging, instrumentation for DNA manipulation, new computer programs for genomic data analysis, the genes expressed in childhood leukemias, the genomic differences that lead to evolutionary changes, the role of host genetic variation in the course of infectious disease, and the molecular basis of specific genetic diseases.