In a prelude to "Hunted," Kraven the Hunter reminisces about how Sasha, Vladimir, and Alyosha were killed by him and Ana for not living up to his legacy.

After cutting a deal with the High Evolutionary who only met with him after some of his New Men were hunted, Kraven the Hunter has 87 clones of him created.

In the case of King Cobra, Rhino, Scorpion, Stegron, Tarantula, and Vulture, they were grouped together as the Savage Six.

Peter Parker is sick due to his encounters with Taskmaster and Black Ant when they tried to capture the Rhino.

He arrives at the place where Black Cat is supposedly held and falls into a trap where there are green gases that make Spider-Man disoriented.

Spider-Man manages to get the upper hand, but hallucinates Mary Jane dying, which causes the Last Son of Kraven to beat him senselessly.

Spider-Man wakes up in Central Park in his black suit where he is attacked by Scorpion with the rest of the Savage Six, Armadillo, Black Mamba, Black Tarantula, Constrictor II, Frog-Man, Gazelle of the Salem's Seven, Gibbon, Hippo, Iguana, Kangaroo, Killer Shrike, Man-Bull, Owl, Panda-Mania, Puma, Slug, Squid, Toad, Walrus, and White Rabbit watch the fight.

[2] Spider-Man is helping the Savage Six, Armadillo, Beetle, Bison, Constrictor II, Dragonfly, Flying Tiger, Frog-Man, Gazelle, Gibbon, Iguana, Killer Shrike, Mad Dog, Man-Bull, Owl, Puma, the Serpent Society, Squid, Toad, Walrus, and White Rabbit escape from the Hunter-Bots, but there is almost no escape as there is a forcefield around Central Park, even Captain Marvel, Iron Man, War Machine, and Vision couldn't break through it.

This forcefield is the remnant of the Planetary Defense Shield that was misused by Hydra back in the "Secret Empire" storyline.

While fighting the hunters, Peter Parker grows worried for Mary Jane, because he fears that his hallucination may become true.

As Spider-Man stays by his side, Gibbon reflects on his life where he even came to the conclusion that Princess Python never loved him.

Vulture creates a lie to the rest of the Savage Six, Armadillo, Constrictor II, Human Fly, Owl, Puma, Razorback II, Scorpia, Snake Marston, and White Rabbit that Gibbon sacrificed himself to give Vulture time to break the forcefield and give him a robot head.

Black Cat uses her bad luck powers to set a leopard free from its cage and attack one of the guards.

Curt also put an inhibitor chip in his spine which prevents him from being violent as well as turn him to human form.

The Pop-Up with No Name is a beer tent at the Queens Night Market that patrons like 8-Ball, Answer, Boomerang, Electro II, Hypno-Hustler, Looter, Mirage, Paper Doll, Screwball, Spot, and Tombstone have been attending ever since the Bar with No Name was blown up.

[6] Black Ant tells Spider-Man that the only way to escape the Central Park is to leave all the villains and by turning small.

The Hunter-Bots are then attacked by the Savage Six, Armadillo, Black Mamba, Dragonfly, Frog-Man, Hippo, Lady Octopus, Puma, Razorback, and Toad when they try to target White Rabbit.

[7] In a flashback, Kraven has Arcade tell Vulture that there is a chance to break the forcefield by killing more Hunter-Bots.

[8] As the Savage Six, Killer Shrike, Lady Octopus, Ox, and White Rabbit continue to take down the Hunter-Bots, Spider-Man is overwhelmed by the Vermin clones.

Curt pleads that Spider-Man rip out the inhibitor chip out of his back, stating that he needs to save Billy and promises to be in control.

Spider-Man relents enough to pass Kraven's test, and the Lizard re-emerges to break free out of the jail.

This enables the Savage Six, Armadillo, Frog-Man, Hippo, Kangaroo, Owl, Panda-Mania, Puma, Scorpia, the Serpent Society, Squid, and White Rabbit to get out of Central Park.

[10] After attending his funeral of his "father," Last Son of Kraven went to the Kravinoff estate, rips off his clothes, and trashed it out of frustration.

Luckily, the Avengers (consisting of Iron Man, Black Panther, Doctor Strange, She-Hulk), Falcon, and the Fantastic Four (consisting of Mister Fantastic, Invisible Woman, Human Torch, and Thing) arrive to subdue them.

Vulture tells King Cobra, Rhino, Scorpion, Stegron, and Tarantula that the Savage Six name has a good ring to it.

Black Ant is found hiding in the bushes by Yellowjacket as he, Human Fly, Razorback, Toad, and White Rabbit plan to take revenge on him.

Black Cat reunites Billy with Martha Connors' lizard form in their sewer home.

Back at the funeral, Chameleon is revealed to be one of the attendees as he is pleased that Kraven the Hunter spared him from the Great Hunt.

"[11] The storyline received generally positive reviews, with critics praising the plot, art, and ending.

According to Comic Book Roundup, Amazing Spider-Man Vol 5 Issue 16 received an average score of 7.1 out of 10 based on 14 reviews.