Huntington Bank's offices moved there from their old building nearby, at the southwest corner of Broad and High, in 1916.

The original southern facade of the Harrison Building is still visible from High Street.

The main, east-facing facade uses fine-grained limestone, with a large central entranceway, multiple belt course, and decorative cornice.

The room features original banking counters, tellers' cages, decorated ceiling, and intricate elevator doors.

[2] The building held the offices of Frederick W. Schumacher, a philanthropist who led the Peruna Drug Manufacturing Company and was an arts patron, and who owned the Frederick W. Schumacher mansion in the city.