Huxelrebe is primarily found in Germany, where the cultivated area covered 396 hectares (980 acres) in 2019, with a decreasing trend.

[1] It is primarily found in the German wine regions Rheinhessen, Palatinate and Nahe.

Higher-end Huxelrebe wines made from riper grapes often have muscat-like aromas in addition.

[2] Huxelrebe was created by German viticulturalist Dr. Georg Scheu (1879-1949) in 1927, when he was working as director of a grape-breeding institute in Alzey in Rheinhessen, by crossing Gutedel (Chasselas) with Courtiller Musqué (Muscat Précoce de Saumur).

[2] Initially known under its breeding code Alzey S 3962, the variety was named after viticulturalist and nursery owner Fritz Huxel (1892-1972), who was the first to cultivate it extensively.