[3] The hyponitrite ions can act as a bidentate ligand in either bridging or chelating mode.

There is a bridging cis-hyponitrite group in the red dinuclear form of nitrosyl pentammine cobalt(III) chloride, [Co(NH3)5NO]Cl2.

[4] Hyponitrite can reduce elemental iodine to hydroiodic acid:[4] Organic trans-hyponitrites R1−O−N=N−O−R2 can be obtained by reacting trans silver(I) hyponitrite Ag2N2O2 with various alkyl halides.

For example, reaction with tert-butyl chloride yields trans di-tert-butyl hyponitrite.

[5][6][7][8] Other alkyl radicals reported in the literature include ethyl,[9] and benzyl.