Initially, there were two sub-regional editions for the East (Norfolk, Suffolk and Essex), and West (Cambridgeshire, Northamptonshire, Bedfordshire, northern Hertfordshire, northern Buckinghamshire (including the City of Milton Keynes), southern Lincolnshire, southern Rutland and a small part of southern Leicestershire).

By 2008, Anglia News opts during GMTV and weekend bulletins had become pan-regional.

The final sub-regional 6pm editions of Anglia Tonight were broadcast on Wednesday 11 February 2009.

[2] On Monday, 14 January 2013, the service was relaunched and renamed as ITV News Anglia.

[3] On 23 July 2013, proposals for a more localised Channel 3 news service were approved - ITV News Anglia reintroduced separate East and West programmes with a minimum of 20 minutes local news content during the half hour 6pm programme, in addition to separate weekday daytime and weekend bulletins for the two sub-regions.