It is a relatively smaller component of Tabernanthe iboga root bark total alkaloids (TA) content.

The percentage of ibogaline in T. iboga root bark is up to 15% TA with ibogaine constituting 80% of the alkaloids and ibogamine up to 5%.

[2][3] Kisantine and Gabonine are thought to be ibogaline's oxidation byproducts.

[4] In rodents, ibogaline induces more body tremor and ataxia compared to ibogaine and ibogamine.

[5] Among a series of iboga and harmala alkaloids evaluated in rats, the study authors found the following order of potency in causing tremors:[5] A subsequent study confirmed these findings.