The Iglesia Parroquial Mayor del Espíritu Santo (English: Main Parish Church of the Holy Spirit), also known as the Sancti Spiritus Main Parish Church or simply the Parroquial Mayor is a historic Catholic parish church located in the province of Sancti Spíritus and the oldest church in Cuba.

Located in the town of Sancti Spíritus, within Sancti Spíritus Province, central Cuba, it is situated on the Plaza Honorato del Castillo.

Built in 1522, the Parish Church of Sancti Spíritus was originally constructed out of wood.

[3] Media related to Iglesia Parroquial Mayor del Espíritu Santo at Wikimedia Commons

This article about a church building or other Christian place of worship in Cuba is a stub.