Illinois 107 heads northeast from the interchange and passes through Griggsville.

The route heads north from Griggsville before turning northwest and passing Perry.

The road terminates at a junction with Illinois 99 in southern Mt.

Illinois 107 is a rural two-lane surface road for its entire length.

[4] In 1992, U.S. 54 replaced Illinois 107 north to the new U.S. Route 36 freeway, which then became Interstate 72.