An autoimmune disease is a condition arising from an abnormal immune response to a normal body part.
Common symptoms include low-grade fever and feeling tired.
[5] Primary immune deficiency diseases are those caused by inherited genetic mutations.
Immunodeficient patients may less frequently develop abscesses of their internal organs, autoimmune or rheumatologic and gastrointestinal problems.
[citation needed] peripheral: Purine nucleoside phosphorylase deficiency