The human male genitals consist of testicles and epididymides, ductus deferentes, seminal vesicles and ejaculatory ducts, prostate, bulbourethral glands, and penis.

[1] The probability of contracting a cancerous development depends on age, ethnicity and the existence, or non-existence, of environmental causation.

Unlike all other genitally situated cancers, the incidence of penis cancer is related to the sexual mode of transmission.

[3] An example of a male genital disease is orchitis.

[citation needed] The three most statistically frequently occurring diseases of the prostate gland are benign hyperplasia (a swelling of the gland, not due to cancerous accumulation), prostatitis (inflammation), and cancer[6] (which is the accumulation of malignant cells in the gland).