[2] Sara Wordsworth said "that In Transit’s 'subway and a cappella' are more than just location and style, respectively; they work as metaphors for life’s painful odysseys and the often unrecognized figures who support us along the way.

"[3] Boxman begins the show by pointing out the amount of time spent in transit by New Yorkers ("A Math Question") and the cast laments how the MTA gets in their way of getting places ("Deep Beneath the City/Not There Yet").

Jane, a struggling actress, wishes that she could be successful and stop temping to make a living which she resolves to do by getting the part she is auditioning for ("Do What I Do").

Later, as Jane has just quit her temping job, she gets a call that she is no longer cast and the role has been offered to Pippa Middleton.

After Trent's mother leaves the city, Steven tells Trent that he loves him anyway and chooses him and they decide to get married that day, and Ali runs into her brother Nate and tells him that she will be moving home to finish her degree, however Nate convinces her to move in with him and finish her degree in New York ("We Are Home").

[7][8][9][10] The musical, directed and choreographed by Kathleen Marshall, premiered on Broadway on November 10, 2016, in previews at the Circle in the Square Theatre with the official opening on December 11.

[11][12] The opening night cast featured Justin Guarini as Trent, Erin Mackey as Ali, Telly Leung as Steven, James Snyder as Nate, Margo Seibert as Jane, Moya Angela as Momma, Ms. Williams, and Althea, and Chesney Snow as Boxman (alternating with Steven "Heaven" Cantor), as well as Nicholas Ward, David Abeles, Gerianne Perez and Mariand Torres.