The southern terminus is the Matthew E. Welsh Bridge on the east side of Mauckport.

The road runs north along rolling terrain in Harrison and Washington counties.

It continues north through hilly country, passing Starve Hollow Lake State Recreation Area in Jackson County and the Brown County State Park.

Highways and Indiana State Roads were all truncated at or rerouted around major cities onto available bypasses in the early 1990s.

It followed Meridian St., Troy Ave., and ended at US 31 and SR 37 at the time (now Madison Ave.).