State Road 445 (SR 445) is a short connector route, just 2.807 miles (4.517 km) long, in eastern Greene County, just north of the small town of Cincinnati.

It then runs east to a four-way intersection where it meets SR 45.

It then continues east, ending at its eastern terminus at exit 104 on Interstate 69 (I-69).

On December 9, 2015, I-69 opened, and SR 445 was extended east to I-69 Exit 104.

The entire route is in Center Township, Greene County.