State Road 54 (SR 54) is an east–west road in Central Indiana in Greene, Lawrence and Sullivan counties.

In Switz City SR 54 meets State Road 67.

After Switz City SR 54 meets U.S. Route 231.

After Bloomfield SR 54 heads east until State Road 43, where SR 54 turns southeast toward Aavoca.

[3] Between 1917 and 1926 the today's route of SR 54 was Indiana State Road 4 and Indiana State Road 30, also at that time the route number SR 54 was routed near the today's route of Indiana State Road 63.