The comic features illustrations by Eric Nguyen as well as a cover art by Doug Mahnke with the story written by William Harms.

[1][2] In the first issue, it is revealed that Moya was working with Kessler on the last stages of the Ray Sphere's Development and also helped fund his research.

While working at an old First Sons research facility in the Neon district, Kessler reveals to Moya one of his test subjects, David, who had been exposed to the Ray Sphere eleven times.

In the present, the government is still covering up the situation in Empire City while over in the Historic District, Cole is mourning by Trish's grave until he is eventually confronted and consoled by Warden Harms.

Meanwhile, over by the Steel Harbour, Moya has gathered several volunteer test subjects with one of them, Lieutenant Poole, being replaced by a mysterious man because of a "blood abnormality."

During that same night, David has escaped his containment from the First Sons' research facility and seeks refuge at his home in North Beach, in the Neon, only to find his wife dead from a drug overdose.

With the Quarantine in its 25th day, Moya continues planning the invasion of Empire City and the capturing of Cole MacGrath.

Zeke reveals to Cole that after he took off with Kessler and the Ray Sphere, he was just locked in a room with "a bed, TV and piss bucket".

In the Neon, troops are flooding the streets and in David's home he has placed the bodies of his wife and daughter on a bed respectfully with crucifixes and lit candles all around the room.

David continues his search to find Cole while killing more Blast survivors (situated in the sewers) in the process.

The media continues their cover up by saying that Military troops are demolishing weak structures of the city to prevent them from collapsing and injuring anyone.

In the meantime, Moya contacts Cole through his cell phone and explains that she sent those troops to lock down the rest of the city and to show him how serious she was.

Moya wanted to use two of who's in the stasis to be in the field to stop David, but the doctor tells her that is impossible and they are not ready.

Moya responded by saying she wasn't asking, but the doctor tells her if they are out of the stasis they will die before they take one step.

Cole returns to the police station and tells them he can't stay because the "thing" was after him and he needs Zeke's apartment keys because he needs a place to sleep.

Moya tells them that one of David's powers is to "smell" people on the genetic level and he is after Cole because he wants revenge for what Kessler did to him.

Then Kessler takes a look at the picture of his wedding day and says "One short sleep past, we wake eternally, and death shall be no more, thou shalt die."

In the Neon District, David rises from the wreckage' still determined to kill Kessler/Cole before he "returns home to his wife and daughter as he promised".

In issue #5, a flashback into the past 4 months prior to the blast shows David's wife, calling his work for the fourth time.

Kessler tells her that if it will make her feel better, she can call the police, but she should consider the fact that her husband simply left her.

He tells another person to send someone to keep an eye on her and get in touch with their contact in the police to make sure they stay out of the facility.

The reporters are initially reluctant, but she convinces them that their station will "move heaven and earth" to get a story of this magnitude.

At the Warren, Zeke, the Warden, and a group of policemen make their move to save Cole, while back at the Neon District in the sewers the reporter interviews the survivors.

Cole jumps out of the ship and Moya argues with the doctor before holding him at gun point and telling him she wasn't asking.

In the miniseries' finale, a flashback shows that a few days before the present, Cole is still recovering from the blast with Trish by his side.

While David is fighting the other Conduits he notices that they stink just like Moya and concludes that her guilt is thick as Kessler's.

Cole remembers how he dropped out of college six credits short of graduation because he got pissed off by how a professor treated one of his friends.

Two days later, the news shows the event of Military conduits and Cole fighting David that was provided by the reporters Phil Maabe and Linda Kaufman.

It also shows how the sick and the injured are forced to live in the sewers, the sinking ship claimed 300 lives, Moya was working without the authorization from her superiors or the US Military, Cole is still at large and the CDC confirms that the quarantine will remain in place for the foreseeable future.

The series shares similarities in regards to the setting of the story, which is focused on a city after a large scale disaster.