Major destinations along the route include Tinker Air Force Base and the heavily populated southside of Oklahoma City.

This western half is the busier of the two sections, serving the Southside area of Oklahoma City and traffic headed to the airport.

[5] Signs were installed in October 2004 designating the western half of I-240 as the Keith Leftwich Memorial Loop in honor of a state senator who had died around that time.

The section of I-240 east of I-35 exists primarily to serve the now-closed General Motors plant and Tinker Air Force Base.

At I-240's eastern terminus with I-40, motorists traveling eastbound on I-240 are forced to merge onto I-40 eastbound—there is no I-40 westbound offramp.

[9] If signed, it will become the longest complete beltway numbered as a single Interstate Highway in the US, supplanting I-275 in Cincinnati, Ohio, at 83.71 miles (134.72 km).

ODOT Director Tim Gatz stated in the Transportation Commission meeting that the numbering change was primarily to aid in navigation using digital mapping and routing applications.

That's common practice across the country, and you'll see that in many of the metropolitan areas, and that update will really be beneficial as far as everything from signage to how do you describe that route on a green-and-white sign.

It is currently a four-leaf cloverleaf interchange that has deemed to be outdated and the improvements will change it to a multi-level interchange with dedicated interstate ramps, turnaround lanes, and service roads for improved city street access in six phases.