Lynes Parkway) is a 6.49-mile-long (10.44 km) auxiliary Interstate Highway mostly in the coastal city of Savannah, located in the east-central portion of the U.S. state of Georgia.

[4][5] The highway also carries unsigned State Route 421 (SR 421) to ensure that all Interstates in Georgia had 400-series reference numbers.

[6][7] I-516 begins in the northeastern part of Garden City, as a freeway continuation of SR 21 (Augusta Road), with which I-516 travels concurrently for its entire length.

The two highways travel to the southeast to an interchange with SR 25/SR 26 Connector (Burnsed Blvd), which leads to U.S. Route 80 (US 80)/SR 26.

The southeasternmost 0.5 miles (0.80 km) downgrades to an expressway with a 45 mph (72 km/h) speed limit, an at-grade intersection at Mildred Street, a right turn lane onto the De Renne Avenue frontage road, and a 35 mph (56 km/h) school zone designation following the frontage road right turn to the Interstate's eastern terminus at Montgomery Street.

The southbound entrance onto Mildred Street is often closed by concrete barriers, as it's primarily used to directly access Hunter Army Air Field from the Interstate.

[11][12] Between 1963 and 1966, I-16 was under construction in Savannah, and the majority of what would become I-516, from Augusta Avenue to its current eastern terminus, was being proposed as SR 26 Loop.

[13][4] Later, in 1966, SR 26 Loop was completed (but not to freeway standards) from just east-southeast of what is now the Veterans Parkway exit to La Roche Avenue, with a proposal to extend it northward through Savannah State University.

[21][22] In 1985, the entire highway from its then-current western terminus at Burnsed Blvd to Montgomery Street was designated as I-516.

The freeway portion was extended westward to the interchange with SR 25 (Burnsed Blvd) and eastward to the current eastern terminus.