[citation needed] Intraperitoneal injections are a way to administer therapeutics and drugs through a peritoneal route (body cavity).

Understanding when intraperitoneal injections can be utilized and in what applications is beneficial to advance current drug delivery methods and provide avenues for further research.

They are mitomycin C, cisplatin, carboplatin, oxaliplatin, irinotecan, 5-fluorouracil, gemcitabine, paclitaxel, docetaxel, doxorubicin, premetrexed, and melphalan.

[11] The results depicted that ketobemidone consumption was significantly lower when patients controlled anesthetic through IP.

In another Phase I clinical trial, patients with ovarian cancer were injected intraperitoneally with dl1520 in order to study the effects of a replication-competent/-selective virus.

In a case of a ruptured hepatocellular carcinoma, it was reported that the patient was treated successfully through the use of an intraperitoneal injection of OK-432, which is an immunomodulatory agent.

This case is a good example of how IP injections can be used to deliver a drug that can help to treat or cure a medical diagnosis over the use of other routes of delivery.

The results set a precedent of how other drugs may be delivered in this way to treat other similar medical issues after further research.

In 2018, a patient with stage IV ovarian cancer and peritoneal metastases was injected intraperitoneally with 12g of mixed cannabinoid before later being hospitalized.

The holder retains the arms of the animal and tilts the head lower than the abdomen to create optimal space in the peritoneal cavity.

Another example of how intraperitoneal injections are used in studies involving rodents is the use of IP for micro-CT contrast enhanced detection of liver tumors.

It was determined that IP injections are a good option for Fenestra to quantify liver tumors in mice.

[20] It was concluded that IP administration should not be used over intravenous therapy due to high radiation absorption in the intestines.

Some of the examples depict situations where IP injections are not ideal, while others prove the advantageous uses if this delivery method.

Overall, many studies utilize IP injections to deliver therapeutics to lab animals due to the efficiency of the administration route.