Iodophors are prepared by mixing iodine with the solubilizing agent; heat can be used to speed up the reaction.
Besides povidone, polyvinyl alcohol, starch derivatives (e.g. dextrin forming cadexomer iodine), chitosan and cellulose have also been used as solubilizing agents.
However, it can leave unattractive orange-brown stains on plastic parts and equipment if left in contact with them.
Diluted iodophor is used extensively in the dairy industry for disinfecting milking parlors, particularly in the United Kingdom.
[6] "Based on a review of the available toxicology data, the [US EPA] has concluded that iodine and iodophor complexes are of very low toxicity by the oral, dermal, and inhalation routes of exposure.