However, the University of Smyrna, the first to be established in the city,[2] never operated due to the Greek defeat in the Greco-Turkish War and the subsequent evacuation in September 1922.

[6] For the same purpose, in September 1920 Georgios Ioakimoglou, lecturer of Pharmacology at Humboldt University of Berlin, was also called to Smyrna to assist Carathéodory in organising the project and to take full professorship for hygiene and microbiology.

[7] Stergiadis promised to support this initiative and indeed, the Greek administration covered the expenses for the foundation, organization and management and granted them a large building, which was half-erected that time.

[8] The building began in 1911 for the School of Union and Progress (İzmir İttihad ve Terakki Mektebi) by the governor of the Aydin Vilayet Mustafa Rahmi Bey.

He also hired specialized technical personnel from Berlin in order to prepare plans for the library’s indoor architecture and detailed designs for the metallic bookshelves.

However, the university would not be able to open due to developments in the ongoing Greco-Turkish War which ended with the Greek defeat and the evacuation of Asia Minor, in September 1922.

In 1936, after the Teachers' College for Males moved to Kızılçullu (It was renamed as "Paradiso" during Greek occupation, now Şirinyer), Buca under the authority of the Village Institutes that was forming at the time, the building was assigned to İzmir Girls' High School [tr]).