Ippolito Borghese (late 16th century – March 1627) was an Italian painter of the late-Renaissance, born in Sigillo (near Perugia).
His training was probably in Rome, where he became a follower of Scipione Pulzone and was influenced by the painterly traditions of Federigo Barocci.
He was influenced by the circle of Mannerist artists active in the Rome of Sixtus V. In 1598 he completed a St. George and the dragon for the Duomo of Ischia.
In 1603, he painted an Assumption of the Virgin for the Chapel of the Palace of Monte di Pietà in Naples.
He painted numerous altarpieces intended for Neapolitan churches such as Santa Maria La Nova, the Bishop's seminary, and Santi Filippo e Giacomo, as well as for churches in surrounding sites such as Lucera, Regoledo, Corigliano Calabro, Amalfi, Caiazzo, San Gregorio Armeno, Meta di Sorrento, and Atri.