Irbesartan, sold under the brand name Aprovel among others, is a medication used to treat high blood pressure, heart failure, and diabetic kidney disease.

[5][6][7][8] Common side effects include dizziness, diarrhea, feeling tired, muscle pain, and heartburn.

[5][9] Serious side effects may include kidney problems, low blood pressure, and angioedema.

[15] Irbesartan is also available in a fixed-dose combination formulation with hydrochlorothiazide, a thiazide diuretic, to achieve an additive antihypertensive effect.

It is jointly marketed by Sanofi-Aventis and Bristol-Myers Squibb under the brand names Aprovel, Karvea, and Avapro.