The Iroquois Lacrosse Arena is a box lacrosse arena on the outskirts of Hagersville, Ontario, Canada on the Six Nations of the Grand River Reserve.

The arena opened in 2004 and does not host hockey games as there is no refrigeration system for ice.

[1] The arena is the home of the six-time Mann Cup winners the Six Nations Chiefs, the five-time Minto Cup winners the Six Nations Arrows, and the seven-time Founders Cup winners the Six Nations Rebels.

The arena is the main practice facility of the Rochester Knighthawks.

The Iroquois Lacrosse Arena hosted the 2006 Minto Cup tournament and the 2009 Canadian Senior B Presidents Cup Championships.