After his bar mitzvah he was sent, as a young prodigy, to Berlin, where he studied the Talmud with his uncle, Rabbi Masos Rintel, from 1769 to 1773.
Whether, as some say, he acquired a fine Hebrew style from Moses Mendelssohn and Naphtali Wessely, or was self-taught – he became one of the foremost hebraists of his time.
In early 1782 Euchel founded, with other young scholars, in Königsberg, the "Chevrat Dorshei Leshon Ever", the "Society of the Friends of Hebrew Literature", and became one of the editors of the periodical "Ha-Meassef" (1783), the organ of the Biurists, where he published regularly.
Of special importance, both to the Jews of his time and as source-material for present-day scholars, was his biography of Moses Mendelssohn, which appeared first in installments in 1788.
The most brilliant example of Euchel's Hebrew style is found in his biography of Moses Mendelssohn, entitled "Toledot Rambeman: Lebensgeschichte Mos.