She was a member of the feminist group Acción Feminista Dominicana (AFD) that helped secure suffrage for women in the Dominican Republic in 1942 under dictator Rafael Trujillo.
By the 1930s she was involved in the national movement for women's rights as a founding member of Dominican Feminist Action (AFD) and active participant in the collective's gatherings and events.
As was a standard tactic of the regime, Mayer found her name on a list of individuals "invited" to form their own party due to their apparent dissatisfaction with the reigning Partido Dominicano.
Mayer responded indignantly that she had no interest in joining any new political collective and would remain, until she died, a loyal follower of the "enlightened" policies of dictator Rafael Trujillo.
As a result of foreign reporters being led to her house in their travels across the country, she was described in multiple English publications variously as a madam, wheel-horse, adventuress, harridan, octaroon, and celestina.