Isabela de Sagua, also shortened as Isabela and nicknamed La Venecia de Cuba ("The Cuban Venice"),[1] is a Cuban village and consejo popular ("people's council", i.e. hamlet) of the municipality of Sagua la Grande, in Villa Clara Province.

The village was founded in 1843 as the port and customs of Sagua and, 5 years later, it was enabled for international import trade.

[1] Located on a peninsula, west of Sagua la Grande River mouth and by a lagoon, Isabela lies by the Atlantic Coast, in front of the Jardines del Rey archipelago.

[2] It is 11 km from Nueva Isabela, 17 from Sagua, 27 from the Mogotes de Jumagua, 36 from Cifuentes and 66 from Santa Clara.

A provincial road links the village to Sagua la Grande and to the "Circuito Norte" (CN) highway.