She became known as a child when she played the rag doll Emília in the children's series Sítio do Picapau Amarelo, joining the cast for six consecutive years.

Still on TV Globo, she continued to gain notoriety by starring in several prominent characters in soap operas such as Bianca in Caras & Bocas, Cida in Cheias de Charme, Giane in Sangue Bom and Manuzita in Verão 90.

[4][10] as Carla in 2009 was the winner of the first season of Super Chefinhos and starred in the feature film Se Eu Fosse Você 2 playing the role of Bia, the daughter of the main couple, Tony Ramos and Gloria Pires, Cláudio and Helena respectively, girl pregnant early boyfriend who hid from his father.

[16] In 2013, she starred in the telenovela Sangue Bom of Maria Adelaide Amaral and Vincent Villari, where she played Giane, a hardcore Corinthians fan.

[17] In 2014, she played her third main role, as Megan in Geração Brasil, repeating the partnership with the authors Filipe Miguez and Izabel de Oliveira.

In 2021, Isabelle participated in the thirteen-episode series As Crianças Que Amamos, on Canal Viva, which features testimonials from actors who began their careers as children and continue in their artistic lives.

[33][34] In 2019, she called on some close friends to help her renovate the house of a humble family that was set on fire in the Rio city of Duque de Caxias.

[38] In February 2014, she began dating singer Tiago Iorc, which only became official in April, at the launch party for the soap opera Geração Brasil.

[45] In November 2012, the DVD "Os Grandes Sucessos Musicais da Novela Cheias De Charme" was released, containing songs recorded by the protagonists, as well as appearances by the soap opera's cast and guest singers.