He then became a Hebrew and Jewish history teacher for a group of youngsters who called themselves Ohave Yerushalaim (Lovers of Jerusalem) and left the yeshiva.
When he was sixteen, he met a group of Jewish socialists, including Mendl Rozenboym, Arkadi Kremer, and Yudin-Ayzenshtadt, and began to acquire a general education.
[3] Ginzburg began attending the Cornell University Medical College in 1896 and received an MD from there in 1900.
He was a staff member for The Forward, writing for them under the pseudonym Der Stechiger (The Satiric One), and contributed reviews on books related to Jewish philosophy, religion, and history for the Yiddish monthly Zukunft.
He wrote, among other books, Der Talmud, Zayn Antshteyung un Antviklung (The Talmud, Its Origins and Development) in 1910, Di Antshteyung fun Kristntum (The Origin of Christianity) in 1917, the two-volume Yidishe Denker un Poeten in Mitlelter (Jewish Thinkers and Poets in the Middle Ages) from 1918 to 1919, and Maimonides in 1935.