Istiaia (Greek: Ιστιαία, pronounced [istiˈe.a], before 1913: Ξηροχώρι - Xirochori[2]) is a town and a former municipality in Euboea, Greece.

Visitor attractions of Istiaia include the Museum of Natural History and the church of Agios Nikolaos.

[6] The municipal unit Istiaia is subdivided into the following communities (constituent villages and population at the 2011 census given in brackets): Istiaia was named after the ancient town of Histiaea, already mentioned by Homer in his Iliad.

Archaeological findings from 2000 BC have been done, suggesting a settlement existed here in the Middle Helladic period.

Its name was changed into Istiaia in 1913, after the ancient town Histiaea.