Jacob Joshua McClain High School was a junior and senior high school in unincorporated Holmes County, Mississippi, United States, about .25 miles (0.40 km) south of Lexington.

[1] It is operated by the Holmes County School District.

Its campus is presently used by Holmes County Central High School.

[1] Originally named the Lexington Attendance Center, it opened in 1959.

[1] In 2015 the high school sectors of McClain, S.V.